Uganda is a landlocked country located in East Africa bordering Lake Victoria. Less than 30 million people live in the country, and 14 million are children below the age of 15. Uganda is a country that has been hit very hard by the HIV/AIDS epidemic and the on-going conflict in the north and eastern Congo. As of 2005, 230,000 children were left orphaned as a result of HIV/AIDS, war in the Congo, and other diseases.

Miryante Community Centre was officially opened in 2021. It is an umbrella organization that provides funding and support for Miryante Foster Care Program as well as St. Gyavira Buyende Home. Miryante Community Centre also provides support for women via the Uganda Women's Network and people with disabilities via Crutches for Africa. 

St. Gyavira Buyende Home was founded in 2019 in response to the overwhelming number of orphaned children with HIV in Buyende District. This program is a foster care program and provides medical care, food, clothing, school fees, and counseling for children with medical conditions while living with families.